Potential roles of neutrophils in regulating intestinal ...
2017-8-31 · Increased infiltration of pathogenic immune cells (e.g., Th1 and Th17 cells) and production of profound proinflammatory cytokines (e.g., TNF-α, IL-12, IL-15 and IL-23) in inflamed intestinal mucosa play a critical role in the pathogenesis of IBD. 41 Several studies have recently reported that Th17 cells can express special chemokine receptors, such as CCR2, CCR4, CCR6, CXCR4, and CXCR6, which …
Get Price